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Breaking News

Expanding Access: Episignatures Now Available in DECIPHER

Expanding Access: Episignatures Now Available in DECIPHER

Making the Promise of Epigenomics a Reality

Explore our breakthroughs in epigenomic research. Our publications in top scientific journals highlight our role in advancing diagnostic approaches for genetic conditions. With a focus on real-world applications, we’re defining the future of genomic medicine.

Expanding Access: Episignatures Now Available in DECIPHER

July 08, 2026

EpiSign Inc. Introduces EpiSign™ v6 with Expanded Episignature Coverage and Enhanced Classification

June 29, 2026

Synthetic Reference Epigenomics: Building a Secure Cloud Framework for Scalable Rare Disease Diagnostics

March 19, 2026
News

DNA methylation analysis of NOTCH1variants reveals the first episignature for non-syndromic congenital heart defects

Gregor Dombrowsky1† , Liselot van der Laan2† , Ananília Silva3 , Jeroen Breckpot4,5 , Enrique Audain1 , Anna Wilsdon6, Michael A. Levy7, Niels Vos8 , Marcel Mannens8 , Jiao Wang9, Anjali Jain10, Robert Lesurf11 , David Winlaw12 , Connie R. Bezzina13 , Mary Ann Thomas14 , Almuth Caliebe15 , Sabine Klaassen16,17 , Felix Berger17 , Sven Dittrich18 , Brigitte Stiller19 , Hashim Abdul-Khaliq20, Ingo Dähnert21, Frances Bu’Lock22, Siobhan Loughna6 , J. David Brook6 , Seema Mital11,23 , Robert B. Russell9 , Thomas Pickardt24, Ulrike Bauer24, Hans-Heiner Kramer25, Anselm Uebing25,26 , Peter Henneman8 , Bekim Sadikovic3,7*† , Alex Postma8,27*† and Marc-Phillip Hitz1*†

Genome Medicine

(2026) 18:2

Publication

EpiSign Inc. Launches METRIC — A Cloud-Based Software Platform Transforming Global Access to Epigenomic Diagnostics

October 15, 2025
News

Ontario Brain Institute partners with EpiSign to advance diagnosis of rare genetic disorders

March 25, 2025
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